Acasti Pharma Inc ACST

Buying opportunity

[Rosmorduc]

Smart money bought big the last month.

Today, idiots and swing traders are dumping without understanding the implication of the news.

Again, this is the best possible outcome we could have expected.

Let the ignorant dump their shares. We'll build a stronger base to trampoline from once Trilogy 2 is released and once diabetic angle becomes the second blockbuster. 

Same smart money who bought big the last month is buying again here at a discount.

[seanj1]

If FDA said redo the whole p3 then that would be the bad news. This drug has no side effect and will help millions. Traders will play their game today and smart investors will buy . Sp is not crashing and recovering with massive volume...

[Francine01]

Agree. There is nothing negative here. They didn't say they refuse, they will see in light of the T2 results. Again, shareholders have no clue of what got wrong with the 5 sites. Its probalby an incorrect understanding of one or two doctors. Finally, the f*** up is only 5 sites and roughly 30 patients on the placebo. Its not the entire study. Stay calm and relax we will know more June 29th

[Rosmorduc]

Francine, there is only minor glitch here which I have highlighted below. Does this mean that Trilogy 2 will not be allowed to sunstract the compromised sites?  If that's the case, this puts us in a position where the additional study will be needed? Thouhgts?  The FDA confirmed that it will require pivotal efficacy analyses for TRILOGY 2 to be performed on the full Intent to

[Stormdog01]

Correct. FDA is not supporting any amendments to T2 SAP. So basically they could have unblinded T2 already in January and not waited for FDA response.  And then why keep the shareholders in the dark for another 10 days before releasing full T1 results?

[Francine01]

My read is that they need to disclose the FULL T2, but in the same release they could exclude the 5 sites, which is minor for T2 and combined with T1 to see the overall picture. The remainig question will the statistical significancy of both T1&T2 without the 5 sites.  Conclusion, its does not change anything if they disclose 100% of T2 results.  June 29th, we will know what went

[Rosmorduc]

I believe in the product based on the history and studies I have read but the way management is handling this is unreal. Every time there is a press release, we end up with more questions without having answers to all our previous questions going back 6 months.  Jeeez. You need to have a strong stomach and a strong conviction as a shareholder in this company. 

[hydrocarbss]

The FDA is bound by their guidance, something that everyone has available... The FDA E9 Statistical Principles for Clinical Trials spells out exactly what to do when this occurs. Lastly, could not the clinical trial personnel figure out that introducing a statin at the same time as testing a trigliceride drug would botch the readouts? Massive, collosial, enormous fail. And Acasti has

[hydrocarbss]

Remember we are dealing with a management team that hasn't put out a well written PR since Rip Van Winkle started napping. I expect the CC to be more of the same.

[Rosmorduc]

We need a new management team I think. Why are they there if they cannot communicate properly and everything is a puzzle wrapped around a riddle.  We have a great blockbuster drug and this management team and technical team has managed to screw things up.