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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by Gessurongon Apr 12, 2024 4:20pm
242 Views
Post# 35986618

From legal papers

From legal papers

Antibe has had both ups and downs, in terms of the development and trial results for Otenaproxesul. It ran into complications in the development and approval of the Drug in September of 2021, leading to Nuance rescinding the license agreement and demanding the immediate return of its U.S. $20 million investment.

Antibe did not return the $20 million, leading to the arbitration, leading to the arbitral award dated February 27, 2024, that Nuance seeks to enforce.

While it has not sought to overturn or appeal the arbitral award in court, Antibe maintains the position that certain aspects of the award were incorrect or inaccurate.
 

Nuance takes the position that, given the findings in the arbitral award, and the arbitral panel's finding that the license agreement was rescinded based on fraudulent misrepresentations on the part of Antibe, its interest in the U.S. $20 million is proprietary. Subject to developments over the next 10 days, counsel for Nuance has advised that his client expects to be pressing that position (and presumably its competing claim to appoint a receiver), when this matter is next before the court.

 

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