IMV Inc IMVIQ

Some of the independent investigator trials

[qwerty22]

Bladder cancer - Dr Fradet
Interesting because this guy worked on Keytruda's pivotal trial in bladder cancer. Dpx-surmage is different formulation to survivac but still contains the Survivin peptides. I found this paper which is about a meeting of Canadian bladder cancer experts from Apr 2020, published Oct 2020. It has the surmage trial listed as pending in table 1. I expect "pending" doesn't mean very much but it should have started based on the original timetable. It seems the grant was for 3 years and they expected pre-clinical and start clinical. Either pre-clinical went bad or Covid delayed things or they are preparing to go clinical. I expect Fradet would want to publish the pre-clinical though, maybe we get it soon idk. Overall hint it's still an active research project but god knows what happened to the timetable.

https://cuaj.ca/index.php/journal/article/download/6887/4638/

Keytruda got authorized on not great numbers
https://www.keytruda.com/advanced-urothelial-bladder-cancer/previously-treated-clinical-trials/

Cervical cancer

This is an HPV E7 based peptide vaccine. I found this paper, it's just a paper about methods but Marianne is on it maybe it shows they are still active around this program. Could be them working up methods to use in the human trial analysis idk.


https://www.tandfonline.com/doi/full/10.1080/2162402X.2020.1851539

The actual trial is meant to be complete next month and the trial is no longer recruiting so maybe we get the data some time next year.

https://clinicaltrials.gov/ct2/show/NCT02865135


The company doesn't seem to have much control on its own timetables but these independent trials are always worse so I guess don't expect much. At least there is a hint they are still active.