IMV Inc IMVIQ

What's up with ASCO?

[Breakthorough1]

There is no abstract. It looks like IMV renounced to present BT results there...

[qwerty22]

They are presenting ovarian https://meetinglibrary.asco.org/record/187578/abstract  

[Breakthorough1]

This is about the MOA. But at the end of April the Basket Trial results were included in the Virtual Program. Now they have disappear. May be they will say something about it tomorrow

[Breakthorough1]

Qwerty22, sorry. May be it is not just the MOA and they add more information about the six patients that still remained and something about new PRs comes...

[alphaseeking001]

Thoughts on the ovarian abstract anyone.  Do we know what the data cutoff was?  Thoughts on ovarian mono moving forward?  I know we're all concentrating on Covid for the moment but I was in this initially for the cancer program and ultimately am in the long term.

[Breakthorough1]

Before February 11th: https://asco.confex.com/asco/2020/cfp.cgi

[qwerty22]

I just can't remember what the basket trial schedule was. This PR from earlier this year suggests that it was just this Ovarian poster that was submitted to ASCO. You sure you're remembering right. https://stockhouse.com/news/press-releases/2020/02/04/clinical-translational-data-supporting-dpx-survivac-mechanism-of-action-to-be  

[Breakthorough1]

Completely sure. Till yesterday a poster was announce in ASCO in the section Development therapeutics-Immunotheray related to the Basket Trial.

[Breakthorough1]

In fact the abstract number was 3104. I have a screen capture I don't know how to post here...

[qwerty22]

I just check the 4th  Q CC. Fred does say there (14mins) that they would provide an ASCO update for the basket trial so you are right. Where is it?

[qwerty22]

any chance they made the Late Breaking Abstract list? That doesn't get revealed until 28th. They had 82 patients enrolled based on the last update. There should be new data to work with for an ordinary presentation. It's hard to understand why they would just cancel.

[Breakthorough1]

Actually the 4h Q CC was the 30th of March. The 23rd of April ("Adelaide capital mini-conference"), it was said basket trial results presented in Q2 (before july). Following ASCO guidelines, to withdraw an abstract you had to have written to them by the 5th of April. It doesn't make any sense to announce it the 30th of March in order to wthdraw four days later: https://meetings.asco

[Breakthorough1]

And also: The ASCO site published the digital program the 29th of April, and the abstract title was there. Could they publish it the 29th if a demand for withdrawal was sent by the 5th of April? MARCH 27, 2020 Abstract Notifications Sent to First Authors APRIL 29, 2020 at 11:00 AM ET Digital Program available, including the release of all abstract titles being presented in the Virtual Scientific

[qwerty22]

  I think some of the analysts were hoping to see some of the six remaining patients that were SD convert to PR in order to increase the ORR. That might be meaningful but my own personal view is the regulators feedback is the crucial point for understanding where that clinical program goes next and that doesn't happen until later this year I think.