RE:RE:Pre clinical haves started see Talems pipeline more FYI about the IPA vaccine if you care to learn more about rationale behind it. I just explained this to a friend so here you guys go: On a side note, the polytope cocktail contains mAbs to target different spike protein epitopes (regions), whereas the covid vaccine does the opposite, it exposes your body to the epitopes of the spike protein, in hopes that your body produces the mAbs to recognize it. As you are all aware, all vaccines that have been produced against covid so far are exposing your body to full length spike protein and triggering your immune system to "randomly" produce mAbs to protect itself against the virus. IPA vaccine approach with Litevax is rationally designed to try to eliminate a lot of that mAbs creation "randomness" that occurs when exposing your body to the full length spike protein via a vaccine. The IPA vaccine will be introducing specific epitopes (regions of the spike) into your body so that your immune system is forced to produce mAbs against a specific epitope (region) as opposed to the full spike protein itself. This is important because of selective pressure that has started to cause the mutagenic escape by the virus to mAbs produced by the vaccine (Pfizer vaccine with UK variant). Certain spike protein regions are more prone to mutation which allows it to escape recognition by the mAbs against itself. The IPA vaccines can get around this by AVOIDING using epitopes (regions that are very prone to mutations) in their vaccine and only selecting spike protein epitopes that have been shown to be very stable (less prone to mutations). At a high level the IPA vaccine rationale has a goal to create "specialist" mAbs against a target region of the protein, as opposed to, random mAbs against the entire full length spike protein. IPA Preclinical vaccine data is determining which combo of selected protein epitopes encourage the strongest creation of "snipers" mAbs against a target region of the spike protein