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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon May 21, 2024 10:02am
82 Views
Post# 36049784

RE:RE:RE: Pelareorep + Paclitaxel = ADC/HER2 failed breast cancer

RE:RE:RE: Pelareorep + Paclitaxel = ADC/HER2 failed breast cancerRegardless of whatever influenced ONCY's decision to target the HER2 failed breast cancer patient population, the HER2 failed population is a large and conclusively identifiable population since they are the same who had been previously identified as having HER2 (positive/negative) breast cancer, treated with an ADC therapy and then ultimately failing on this same therapy.

These failed breast cancer patients could benefit from the sequential introduction of ONCY's pelareorep with the ADC and then an immune checkpoint inhibitor. 

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