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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Jun 07, 2024 10:23am
95 Views
Post# 36077415

RE:RE:RE:RE:RE:ONCY's pelareorep can provide a fine T-cell boost for ADCs

RE:RE:RE:RE:RE:ONCY's pelareorep can provide a fine T-cell boost for ADCsIn February 2024, AbbVie closed a $10.1 billion deal acquiring ImmunoGen, an ADC-focused biotechnology company headquartered in suburban Boston. 

June 07, 2024 - Abbive reported on the 
Phase II PICCOLO trial from its newly acquired antibody-drug conjugate Elahere (mirvetuximab soravtansine) from ImmunoGen in folate receptor-alpha-positive, platinum-sensitive ovarian cancer. 


Elahere met its primary efficacy endpoint, eliciting a 51.9% objective response rate in heavily pretreated patients. The median duration of response, one of PICCOLO’s key secondary outcomes, reached 8.25 months.

https://www.biospace.com/article/abbvie-sees-early-roi-on-10b-immunogen-buy-with-phase-ii-ovarian-cancer-win/

https://www.immunogen.com/wp-content/uploads/2022/03/SGO-2022_PICCOLO-TiP_Secord_vF.pdf
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