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Pressure Biosciences Inc PBIO

Pressure BioSciences, Inc. is engaged in providing broadly enabling, high pressure-based solutions for a range of industries, including biotechnology, pharmaceutical, nutraceutical, cosmeceutical, and agrochemical, as well as food and beverage manufacturing. The Company's enabling platform, Pressure Cycling Technology (PCT), utilizes alternating cycles of pressure to control bio-molecular interactions (such as cell lysis and biomolecule extraction) safely and reproducibly. The Company's BaroFold technology platform allows it to enter the bio-pharma contract services and GMP manufacturing equipment sector. It has also developed the scalable and pressure-based UltraShear Technology platform, which allows for the creation of stable nanoemulsions of otherwise immiscible fluids. It also allows for the preparation of homogenized, extended shelf-life or room temperature-stable low-acid liquid foods that cannot be preserved using existing non-thermal technologies.


OTCQB:PBIO - Post by User

Post by AveragePennyon Apr 27, 2022 12:27pm
52 Views
Post# 34635964

Pressure BioSciences Announces Early Access Program for UST

Pressure BioSciences Announces Early Access Program for UST

SOUTH EASTON, MA / ACCESSWIRE / April 27, 2022 / Pressure BioSciences, Inc. (OTCQB:PBIO) ("PBI" or the "Company"), a leader in the development and sale of broadly enabling, pressure-based instruments, consumables, and specialty testing services to the worldwide biotechnology, biotherapeutics, nutraceuticals, cosmetics, agriculture, and food & beverage industries, today announced the initiation of an Early Access Program (effective July 1, 2022) for the use of its revolutionary Ultra Shear Technology™ ("UST™") platform for the processing of oil-based active ingredients into highly stable, water soluble, long-term stable nanoemulsions.

In September 2021, and reinforced several times since, the Company announced plans for the commercialization of its revolutionary UST platform. Under this plan, commercialization activities are to begin with the opening of two fee-for-service, GMP-compliant tolling centers in the 2022 fourth quarter. These centers are to be located in the Boston and San Francisco areas. Good progress continues to be made in this effort.

Importantly however, PBI has been experiencing more immediate demand for UST-processed nanoemulsions. Although the UST platform systems and laboratory space required for the tolling sites will not be available until later in 2022, the Company currently has three working benchtop, small-capacity systems (BaroShear MINI) and expects to soon finish the manufacture of both a mid-capacity BaroShear K45 and a large-capacity BaroShear MAX (capable of very large production runs). Propelled by this very welcomed demand to use the UST platform, and aware that such use could help to accelerate the trajectory of commercial proof of principle, production engagement, and conversion into long term processing relationships with a diverse group of prospective partners in the nutraceutical, health and beauty, agrochem, and food/beverage industries, PBI has decided to open up a program to allow early access to the UST processing system.

Mr. John B. Hollister, Director of Sales and Marketing at PBI, addressed the burgeoning demand for access to PBI's UST platform for processing valuable oil/water emulsion-based products in multiple major markets: "We have announced our plans to have commercial toll-production UST-processing capacity operational on the East and West coasts of the USA by Q4 2022. Since announcing this, we have worked closely with a number of companies on formulating some of their products. As a result, the demand to serve initial contracts for pilot-scale production of nanoemulsions in nutraceuticals, cosmetics, health and beauty care, and agrochemical markets has become particularly intense and is growing. We anticipate the announcement of at least two significant relationships and contracts within these sectors during Q2 2022, for which early small-batch production capacity can be pivotal to accelerating the commercialization phase to follow."

Dr. Alexander Lazarev, Chief Science Officer at PBI, said: "UST, by design, is a scalable and precisely controlled process that allows us to "dial in" and routinely deliver sub100 nm nanoemulsions of desired characteristics. Resulting oil droplets become smaller than the wavelength of visible light, at which point the previously cloudy/opaque emulsions become transparent nanoemulsions. More importantly, oil-soluble bioactive molecules are now in nano-droplets so small that they become more readily absorbable and bioavailable. Taste and smell characteristics are similarly magnified, while textures are ultimately transformed into silkiness and lower viscosity. Most microorganisms are also destroyed in the process, yielding room-temperature stability against spoilage without a need for preservatives. Moreover, nanoemulsions are easily sterilized by filtration, which makes them ideal media for pharmaceutical drug delivery. These nanoemulsions exhibit remarkable stability against physical separation when prepared using our minimal custom formulations of plant-based, non-GMO, non-allergenic, organic/green natural stabilizers designed for clean label products."

https://www.accesswire.com/699082/pressure-biosciences-announces-early-access-program-for-ust-nanoemulsion-processing

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