RE:RE:Important Notice!!!!!!....Only post in BB if you think it'sGrapeguy, regarding PBI-4050 being used in conjunction with other drugs. Think about it from the point of view of the patient. Why would they (and their doctors advising them) agreed to go off a drug that is doing something for them to try a drug that might work based on some rat studies. We can bet on 4050 with our investment money, but for them the bet is their health.
4050 has passsed a 1b showing it is safe in patients, so there is little risk of side effects from the two drugs. To me it just makes sense to design a trial this way. The T2+MS trail was the same way. I suspect this approach to be the norm in trails.
IMHO