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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Post by Gbathaton Dec 12, 2020 8:39am
126 Views
Post# 32092656

market still open for tau antibodies... nature article

market still open for tau antibodies... nature articlehttps://www.nature.com/articles/d41573-020-00217-7

Failure of first anti-tau antibody in Alzheimer disease highlights risks of history repeating
A wave of tau-targeted agents is progressing through the clinic, hoping to avoid the negative results from a first-in-class trial of a tau-targeted antibody.



I came across this article with an internet search for "Neil Cashman" posted in the last week.  The search engine link quotes Dr. Cashman, but I cannot access the article right now.  

It appears to be a summary of the ongoing efforts to develop antibodies for tau.  I'm trying to find which study the article title is referring to... looks like a PH 1 that did not go well.


Bottom line: more opportunity for ProMIS
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