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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Post by Gbathaton Dec 14, 2020 9:09am
196 Views
Post# 32098386

PMN update- 2020 in review

PMN update- 2020 in reviewhttps://promisneurosciences.com/news/year-in-review-looking-forward-to-2021/

Here is the 2020 review from PMN's Dr. Goldstein.  It provides a good overview on the status of current programs.  It also has some new analysis on aducanumab, still leaning towards approval.

It mentions external challenges with regard to PMN310 capital raise.  Not having any optics on who they are targeting, it is hard for me to assess the validity of these statements.  Obviously COVID has been disruptive with regard to prioritization in pharma.  Maybe some of the companies with large COVID revenues and lots of cash already on hand (i.e. Pfizer) would be a good target.

They have mentioned that $10M is the ask for PHI support.  But it is worth contemplating that PHII and PHIII are likely much more costly, so at the end of the day, it's not just an ask for $10M (from a corporate partner/investor planning perspective).
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