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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Post by Gbathaton Dec 16, 2020 5:02pm
193 Views
Post# 32123171

bcneuro

bcneuro

https://bcneuro.ca/research/

Affinity/Binding Measures of Antigen/Antibody Interactions Using BIAcore™ (Antibody Screening)

SARS-CoV-2 Serological Assay

We are presently at work on producing, testing, and validating antibodies for SARS-CoV-2 through the use of surface plasmon resonance (SPR) technology.  It is our aim to develop a serological assay that would supplement the existing overstressed testing apparatus, helping to determine patients’ illness and immunity status, thus allowing earlier identification of infected individuals, as well as those who have already been sick and recovered alike.  This would permit a more precise tailoring of our national quarantine and isolation protocols, helping to flatten the curve, as well as grant a sense of relief to the previously infected individuals dedicated to working on the front lines to combat this virus, who may have been asymptomatic during the course of their illness.  Knowledge of who possesses in their sera the requisite antibodies to produce immunity to future COVID-19 exposure can produce more effective allocation of resources, human and otherwise, in hospital settings, as well as set minds at ease, providing a sense of security for these brave individuals in these uncertain times.


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