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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Comment by Gbathaton Jul 03, 2021 7:42am
148 Views
Post# 33489324

RE:Don't expect Much

RE:Don't expect MuchIf corporate management and share structure is the impediment, then we need to do a JV with big pharmacy (Big P) that is structured to benefit both parties, protect both parties, and maximize efficient operation of the JV.

Scope: PMN 310 development and commercialization

Big P contribution:  $20M for Phase 1 funding plus a commitment for Phase 2-3 funding contingent on quantifiable technical and market analysis metrics. 

Big P gains:  10% ownership of ProMIS.  80% of JV earnings. Control of JV management.

PMN contribution: Exclusive license for PMN310 in humanized form, as well as future vaccine formats.  IND enabling work for Phase 1and technical support for all material  issues pertaining to PMN 310.

PMN gains: 10% of JV revenues (licensing fee) plus 20% of earnings.

So, how would that work out if said JV captured $10B per year in sales?  PMN would get $1B off the top.  Assuming a profit margin of 25%, Big P would get about $2B in earnings and PMN would get another $500m.

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