RE:Nothing like a bit of fear to promote PMN310 science table setter becoming a red carpet... hopefully they don't slow down the IND approval due to this and have a good understading of the science behind PMN310.
https://www.science.org/content/article/scientists-tie-third-clinical-trial-death-experimental-alzheimer-s-drug
"Although lecanemab targets a soluble version of beta amyloid, it also binds to the extracellular beta amyloid “plaques,” considered a hallmark of Alzheimer’s. About half of Alzheimer’s patients have a condition called cerebral amyloid angiopathy (CAA), in which beta amyloid plaques replace the smooth muscle of blood vessel walls. When antibodies such as lecanemab strip away those plaques, blood vessels can become inflamed and weakened, increasing a person’s susceptibility to ARIA."