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SCYNEXIS Inc SCYX

SCYNEXIS, Inc. is a biotechnology company. It is pioneering medicine to overcome and prevent difficult-to-treat and drug-resistant infections. It develops antifungal platform fungerps, a novel class of antifungal agents called triterpenoids, that are structurally distinct glucan synthase inhibitors and have generally shown in vitro and in vivo activity against a range of human fungal pathogens, such as Candida and Aspergillus genera, including multidrug-resistant strains, and Pneumocystis, Coccidioides, Histoplasma and Blastomyces genera and common mucorales species. Ibrexafungerp is the first representative of this novel class of antifungals with additional assets from the fungerp family, including SCY-247, in preclinical stages of development. The United States Food and Drug Administration approved BREXAFEMME for treatment of patients with vulvovaginal candidiasis, also known as vaginal yeast infection, and for the reduction in the incidence of recurrent vulvovaginal candidiasis.


NDAQ:SCYX - Post by User

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Post by JonathanJSmithon Aug 02, 2022 8:23am
204 Views
Post# 34865127

Can we expect additional Rx's to the fold this winter?

Can we expect additional Rx's to the fold this winter?It's been a while and I've had some time to digest several variables; here are some of my findings:

These guys are still trading well below cash, which is interesting. According to their most recent 10-Q, they had about $135MM in cash (after the $45MM financing).  After looking at their pipeline timeline and respective indications, the next catalyst occurs in late November (rVVC); furthermore, there remains a potential Hansoh Pharma payment (don't forget, they can earn up to $112MM in milestone payments) in FY2023, and an EU partner agreement. If the latter is consummated, they may not need further financing. We'll see if they can deliver.

Insofar as recurrent VVC, it appears that with the sNDA, if approved, might provide up to an additional 540K Rx's to the fold. Here's an outdated corroborative article illustrating some numbers vis-a-vis rVVC (my guess is that today, the numbers are higher)...

https://today.wayne.edu/medicine/news/2018/07/03/new-study-shows-138-million-women-suffer-from-recurrent-candida-or-yeast-vaginitis-numbers-expected-to-increase-30164

Cheers,

JJ
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