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Antibe Therapeutics Inc(Pre-Merger) T.ATE

Alternate Symbol(s):  ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


TSX:ATE - Post by User

Post by mstrmndon Feb 28, 2020 3:04pm
305 Views
Post# 30748607

Naproxen vs. Placebo - Predictable Results Coming - BUY

Naproxen vs. Placebo - Predictable Results Coming - BUYhttps://twitter.com/ndaloisi/status/1233456005406654464?s=20

The core active pharmaceutical ingredient and molecular structure is Naproxen.  With the incredibly robust data this company already has, next steps are as follows (already set in motion and very predictable):

1) In 2 weeks - Trial Completion Annoucement
-It's only going up
-Also because of the protracted nature of the study, the safety of the drug is a foregone conclusion

2) In 4 weeks - Results Announcement
-It's only going even more up

3) In 6 weeks - Read out
-And these results are already very predictable if you can understand the clinical trial methodology.  As I've mentioned before, the power of the study is so large (completing the trial within the timelines was the risk), I am expecting equally as impressive study results as last year based on the p value.  Why - because we are comparing naproxen + hydrogen sulfide versus nothing which is a guaranteed win. 

Great job Antibe!  The world desparately needs ATB-346.  There's an immediate need in medicine and it penetrates the market to billions wonderfully because of one thing - it's NSAID ulcer healing properties are out of this world.  This is New England Journal of Medicine worthy for Phase 3.  

#1 NSAID in the world and the strategic execution of this purely for safety purposes will take this to #1 rapidly.  Think about it, for pain (ie. osteoarthritis) the revenue streams for Aspirin, Advil, Naproxen, Aleven, Motrin, etc. are immediately disrupted by the #1 player worldwide that no one else can claim - better safety.  Who cares how much it works more or less than Naproxen alone - not upside, its downside - the side effects from NSAIDS, #1 GI ulcers do kill and this medication will be #1 Gastroenterologist recommended NSAID globally. 

Purely from the medical side - BUY 

Will leave the rest to ATE.V to prove me wrong.  Well played Antibe, wonderful execution - I see the hole you fill immediately, and you're heading into a pharma bidding war.  




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