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Antibe Therapeutics Inc(Pre-Merger) T.ATE

Alternate Symbol(s):  ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


TSX:ATE - Post by User

Post by mstrmndon Dec 18, 2020 10:38am
219 Views
Post# 32139603

Amalgamated Valuation > Dilution Concerns

Amalgamated Valuation > Dilution ConcernsSo in my conversations with Dan, the real value is the IP and patents that are in the holding company. 

I know for a fact that ATB-346, ATB-352, ATB-340 are the tip of the iceberg and these guys have patent rights for a whole lot more.  They have IP rights to agents for Inflammatory Bowel Diseases (Crohn's Disease and Ulcerative Colitis) in the holding company (ATB-429 - Mesalamine analog) and I've heard internally the suspected efficacy.  How are they going to monetize the patent rights? Likely part of the entire partnership package.  

This might sound like a joke to most people that are not in the know, but I agree with Mugs that the net value of the holding company patents + proof of concept from the 2A/2B trials should be north of $10B and could be in the range of $50B.  

Bottom line, if you understand how to make new molecules for patenting, Antibe Holdings likely has a every NSAID known to man + H2S in there, and with my comment on ATB-429 (Mesalamine), it shows you they may have added H2S to a whole LOT more than NSAIDS where there's less of a concern about GI safety and more about superiority of efficacy with the addition of a hydrogen sulfide moiety based strictly on deficiencies and needs identified in medicine where there's a clear need.

I love this announcement. Can't believe people can still get in at this price, where the pre-Phase 2 risk is all gone but pretty close to the same price. 

Do your own DD.  GLTA and to all the longs, good times are definitely ahead.  To me, this is the first sign that a partnership is perhaps closer than we think.

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