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Antibe Therapeutics Inc(Pre-Merger) T.ATE


Primary Symbol: ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by MrMugsyon Apr 23, 2021 12:27pm
102 Views
Post# 33055500

RE:A call for potential treatments

RE:A call for potential treatments
Quetzaly215 wrote:

Health professionals have become alarmed about Parkinson’s disease. About 10 million people struggle with it worldwide and roughly 60,000 people are diagnosed with it in the U.S. alone every year.The need for these potential treatments to help individuals who suffer from these disease might be at the hands of these other firms that recently announced the successful completion of a Type B pre-Investigational New Drug meeting with the U.S. FDA!

Parkinson's disease occurs when nerve cells, or neurons, in an area of the brain that controls movement become impaired and/or die. Normally, these neurons produce an important brain chemical known as dopamine. When the neurons die or become impaired, they produce less dopamine, which causes the movement problems of Parkinson's. Although some cases of Parkinson's appear to be hereditary, and a few could be traced to specific genetic mutations, in most cases the disease occurs randomly and does not seem to run in families. 
 
 
The groundbreaking  solution to possibly treat levodopa-induced dyskinesia in Parkinson’s patients (LID-PD) have been one of the goals of these other companies that recently announced the successful completion of  a Type B pre-Investigational New Drug meeting with the U.S. FDA regarding their proposed Phase 2 clinical study of ketamine based LID-PD treatments. While the Parkinson’s treatment story is undoubtedly impressive, they are also helping to treat MDD, or Major Depressive Disorder. According to Global Data, this market could be worth roughly $7.87 billion by 2029 and have been shown to enhance the antidepressant effect while having the potential to significantly reduce the known adverse side effects of ketamine. Sponsored post. Check disclaimer on profile.


Where the future of Alzheimer's is (with H2S), I'd be betting an indication for Parkinson's too my friend.  Let's just focus on keeping the brain cells younger for longer with Antibe's approach.

: )
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