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Antibe Therapeutics Inc(Pre-Merger) T.ATE

Alternate Symbol(s):  ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


TSX:ATE - Post by User

Comment by MrMugsyon Jan 16, 2024 9:11am
113 Views
Post# 35828619

RE:RE:Upcoming Discussion ...

RE:RE:Upcoming Discussion ...

Regardless of easier or harder - both acute and chronic are huge markets on their own.  Also, acute is a short window for painkiller usage which makes OTENA a perfect candidate.  Chronic is more complex in regimen design w.r.t. the liver (IMO) and success in chronic will come from success in acute ... first.

Remember - as far as I'm concerned ... I'll take a chronic flare-up drug in the end.  I'm not selfish ... hahaha!  

Also remember - what some call a debacle may have been unavoidable.  If you can't see the same effect in animals as in humans then you are at a disadvantage.  

The difference may still prove to be the elegance in the pivot.  This pivot has a risk-reducing effect that may come with 20 year IP ... in double the market size.  That's the bet I made in 2019 and going directly to 20 years patent was my hope.  I didn't really get excited about a 5 year patent.

So ... back to our fully-funded P2 ... that's the key that can drive excitement in various directions.  I think we need Jan 18th in order to really understand where we're going.  We need it (along with P2 results) to excite potential partners.   

Let's see.

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