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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by jimsenioron Feb 18, 2023 8:06pm
190 Views
Post# 35294021

RE:RE:RE:RE:Phase 1 Colorectal Cancer demonstrated 93% clinical benefit

RE:RE:RE:RE:Phase 1 Colorectal Cancer demonstrated 93% clinical benefit @buck. Thank you so much. You prompted me to look up something that clarifies the status of GOBLET; at least for me. I had forgotten about the following. ONC/ONCY release March 31, 2022. I do not know how to post a release so I shall leave that for another.

The gist is as follows. As of the above date the safety run-in for Cohort 3 (3 patients) had been successfully completed. Cohort 2 and 4 did not include safety run-ins so all 4 cohorts were full steam ahead. Pancreatic we have some news. The other 3 cohorts cannot be far behind. I do not want to sound like a pumper (I know how difficult it is to bring these trials home) so all I shall say is that there has been a cocoon around GOBLET and that is likely a good thing. Cheers
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