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Bullboard - Stock Discussion Forum
Oncolytics Biotech Inc
T.ONC
Alternate Symbol(s):
ONCY
Healthcare
Biotechnology
Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune...
responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.
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TSX:ONC - Post Discussion
Oncolytics Biotech Inc
> ONCY's Pela + GM-CSF + SOC more effective than SOC in GBM
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Post by
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on Apr 11, 2022 1:43pm
ONCY's Pela + GM-CSF + SOC more effective than SOC in GBM
April 8, 2022
/CNW/ -- Oncolytics Biotech
®
Inc. (NASDAQ: ONCY) (TSX: ONC) today announced positive long-term survival data from ReoGlio, an investigator-sponsored phase 1b trial evaluating the combination of pelareorep and granulocyte-macrophage colony-stimulating factor (GM-CSF) alongside standard chemoradiotherapy and adjuvant temozolomide for the treatment of glioblastoma multiforme (GBM). The results, which are the subject of a presentation at the American Association for Cancer Research (AACR) Annual Meeting, show a substantial and durable efficacy signal in newly diagnosed GBM patients and demonstrate the safety and tolerability of the studied treatment combination in this indication.
Evaluable patients treated with pelareorep at dose level-2 (3x10
10
TCID
50
) had a median overall survival (mOS) of 16.1 months and a 24-month survival rate of 50% (n=6)
https://www.oncolyticsbiotech.com/press-releases/detail/568/oncolytics-biotech-announces-positive-long-term-survival
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Comment by
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on Apr 17, 2022 1:59pm
An OV + GM-CSF doublet is proving to be effective in combination with both checkpoint inhibitors and SOC.
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