Oncolytics Biotech Inc T.ONC

Waiting...

[SundayMovies]

So far so good. The longer the wait the better the results. After all, we are talking about survival here.
Live on. Live longer. The pressure is building up... Then the rocket launch.

[Quentin30]

You know what.. When investors were waiting to hear about results from ONCY's first Phase III trail for head & Neck cancers, Brtad Thomson (then CEO), reassured investors that the survival curve was still progressing... and I think results were 12 months later than anticipated. From the numbers previously presented, in essence the company was waiting on data from just one or two patients.

[inthno]

It was a huge mistake in the trial design that caused the first phase 3 to not be successful so one would think that the company has learned from all of the past mistakes when designing the next hopeful upcoming phase 3 trial. But lets just hope we all get the BO and we don't have to worry about the trial design or the 4 years to run the trial.

[westcoast1000]

inthno, As recall those days, Brad Thompson was both overconfident and constrained by lack of capital. He also felt their team could just figure out what to do and somehow do it. After they collected the data (I seem to remember some shapy aspects of that) the FDA insisted they segment the data into two groups. As a result they could not get statistical significance at .95 although it was very

[Quentin30]

Hi Westcoast1000. Thanks, as my landing page here, I actually have one of your comments from back in 2018. It was just after a conference call, and you were optimistic that we wouldn't have to wait long, as Matt and Co would be focusing on partnering. 4 and bit years later and here we are... ALL of us, just hoping... If Pfizer is able to see the data maturing in real time, and they are at 45

[westcoast1000]

Quentin, Yes, I have been thinking they are about to partner for a long time. But over the last year or so the time llines have been more realistic. At least we know what events we are waiting for.

[inthno]

Hello Westcoast, there were indeed issues with the trial design and even though they had a top investigator helping them it did not work. Problem is that people were being removed from the trial that should not have been as a result of a higher than normal temperatures in the patients which is actually a sign of the virus working and many of those patients were removed. Also at that time they were

[westcoast1000]

Hi inthno Yes I recall now they threw out people who had a temperature response. So that alone made our trials less likely to work.  I personally would not call breaking the data into sub groups data mining, because they are setting that out in the design of the trials. For example they are now (ow will be ) focusing only on people with the right biomarkers, when formerly they would have

[inthno]

Hey Westcoast I m still thinking good things ahead and as you said use of biomarkers. One issue is that in all the presentations it always says POTENTIAL USE of biomarkers. I would hope that after 4 years with aware 1 that it is the use and not otential use. Please onc do not be stubborn with price and just sell this for 2+ billion or more and be done.

[Lesalpes29]

2B+ is my target. But if they want to pay more I will take it! I'm not a big dreamer. GL

[fox7mf]

I wouldn't turn my nose up at $2b + usd, but I remain ardent in my belief that the accepted offer will be more. But I get it. Every long gets it. It would just be nice for this journey to come to an end, and for BP to get Pela to market.

[westcoast1000]

Inthno, I certainly agree they have not been forthcoming about whether biomarkers are now considered "settled" and part of the trial and approval process. As for the price of a buyout, I have indicated I am already pretty old for making investments in risky startup and hope for a successful conclusion sooner rather than later.

[inthno]

Remember that the thing we have been told about the Bracelet results is that we will hear nothing until the major conference that they want to report at so even if they have everything done as of today we still have to wait until the conference, that was made very clear by Matt. Big thing is will the CI make the difference enough in the trail for pfizer to step up or will the os to date by itself

[Buckhenry]

love ur rationale.... in the meantime the stock price keeps going down.