Today is World Hemophilia DayWorld Hemophilia Day is an international observance held annually on April 17 by the World Federation of Hemophilia (WFH). Hemophilia is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. Men usually suffer from this disease, women act as carriers of hemophilia and can give birth to sick sons or daughters-carriers. The worldwide incidence of hemophilia is not well known, but estimated at more than 400,000 people. Approximately 75 percent of people with hemophilia around the world still receive inadequate treatment or have no access to treatment. The most famous bearer of hemophilia in history was the English Queen Victoria. Queen Victoria, through two of her five daughters (Princess Alice and Princess Beatrice), passed the mutation to various royal houses across the continent, including the royal families of Spain, Germany and Russia. Victoria's youngest son, Leopold, was affected by the blood-clotting disease. He died from blood loss after he slipped and fell. Alexei Nikolaevich, the youngest child and only son of Emperor Nicholas II and Empress Alexandra Feodorovna (Princess Alices daughter), was born with hemophilia. For this reason, hemophilia was once popularly called "the royal disease".