Sernova Corp T.SVA

Abstract of presentation in January

[MarkMcFly]

...

Results: Seven patients were submitted to 21 study related surgeries with a wound infection in 2 patients after SCP implantation with only one patient requiring device excision. The first subject presented with persistent stimulated serum C-peptide at 6 months after 1st and 2nd ITx into SCP. After 2ndITx, glucose control improved substantially including reaching optimal target values for CGM with only 5% of Time Below Range (TBR). Subsequent intraportal ITx allowed for insulin independence currently maintained for over 15 months. The second patient at 3 months after 2nd ITx had positive stimulated serum C-peptide (0.48 ng/mL) with reduction of HbA1c from 10.6% to 7.6%, decreased insulin requirement from 49 to 28 u/day, improved CGM with TBR <4%, and reduction in Time Above Range (TAR) from 76% to 48%. To date, stimulated C-peptide has been detected for over 9 months. Three additional patients recently received ITx and await evaluation.

 

Conclusion: Persistent islet graft function with sustained blood levels of C-peptide, reduction of HbA1c, improved CGM parameters, reduction of SHEs, and decreased total daily insulin requirement was achieved in the first 2 patients after ITx into SCPs implanted into abdominal wall. Significantly improved islet engraftment and clinical outcomes occurred using a modified approach for ITx into SCP.

https://www.researchgate.net/profile/John-Fung-3/publication/356594439_3075_Modified_Approach_Allowed_for_Improved_Islet_Allotransplantation_Into_Pre-vascularized_Sernova_Cell_PouchTM_Device_-_Preliminary_Results_of_the_Phase_III_Clinical_Trial_at_University_of_Chicago/links/61af64ab68f38b79131cb9ad/3075-Modified-Approach-Allowed-for-Improved-Islet-Allotransplantation-Into-Pre-vascularized-Sernova-Cell-PouchTM-Device-Preliminary-Results-of-the-Phase-I-II-Clinical-Trial-at-University-of-Chicago?origin=publication_detail

[BioTeck]

Oh so they are releasing data a whole year later about ONE other patient. Meanwhile the search for patient 7 continues. Maybe next year we will get an update on patient 3 in January. I can see why no pharma wants to sign. .

[MoneyMouth]

Its old data regardless, it mentions 15 months insulin independent and now that person is over 20 months insulin independent. 21 months by the time this is presented. Who knows what other data could have been gathered in the last 6 months. Additionally, you cant comment on pharma because they would be conducting their own research, independent of the study

[MoneyMouth]

Also, take a look at page 13 of the December investor deck on Sernova's website. It shows 3 patients passed the "top up infusion" mark...

[bull1986]

Great results! Looking forward to up-to-date information from Dr.Witkowski! Take note of page 13 in December presentation. 

[Charly50]

I can't imagine it for the life of me,  that a recognized expert, on January 13, 2022,  in front of more than 600 transplant professionals, if there weren't very positive things to report.   The American Society of Transplant Surgeons represents approximately 1,900 professionals, regulators and pharmaceutical representatives dedicated to excellence in transplant

[Mercuryfilling1]

 I actually agree with you Charles (but tell your translator not to quit his day job).  Will Witkowski's update include nothing new? Just a steaming re-hash of old news? Unlikely as his name isn't Philip, it's Piotr.   

[Canada2016]

Bioteck the one who will always be the guy who was shouting bragging in fact he sold a million shares at 40 cents when within a week or two after it went to nearly 3 bucks.bud you don't have that many shares and there's been enough volume where you could have unloaded in the last months. Your all talk on a bullboard name calling like a little immature brat. It's going up that's the

[MustangSalley]

Canada, They will need the 7 th patient to complete the trial . That is a red line . They will need more patients perhaps not btittle diabetics , but Type 2 for more clinical trials . It's a long way before you can get your yacht Canada , unless there is a premature buyout but I don't think that happens without results first . It will be several years before they have conformal coating

[MoneyMouth]

You guys don't even read the official communications from Sernova i.e. the latest slide show... it clearly states anticipated conformal coating in 2023, so yes atleast a year+. Why you guys can't wait patiently like the rest of us is your own problem. If your missing other opportunities because of this stock, well then I guess you are a bad investor hey?

[MustangSalley]

Mouth, I can show slides from the past where it said 7 patients and trial would be concluded in a year . That was 2019.  If you believe everything management says on a slide ..... like dsu options are for new hirers..... then I got some swampland in Florida for you . 7 million options for Toleikis , 5 million for Sweatlow ... they granted themselves over 40 million options at the last AGM

[Metalsguy1]

MoneyMouth. Wipe your chin and dust off your knees. Wait patiently for 2023 when IR people in the past have misrepresented the staus of earlier coating approaches? Until there is verifiable scientific proof that this latest coating works in humans, your breath just smells like the a$$ you are talking out of.

[Metalsguy1]

MoneyMouth. Wipe your chin and dust off your knees. Wait patiently for 2023 when IR people in the past have misrepresented the staus of earlier coating approaches? Until there is verifiable scientific proof that this latest coating works in humans, your breath just smells like the a$$ you are talking out of.

[Mercuryfilling1]

Metallergic...you're, your posting twice, twice. Stop getting distracted by that giant inflatable shlong Bio keeps nudging your way. Take moment and breath...you'll always be a wingman so it's not necessary to answer on the Big B's behalf every time, time.  He's a big, big,  boy, boy. Merry Grinchmas 'allergic.

[BioTeck]

So many haters. I'm not sure why you're so angry with my posts. Just posting facts. Management makes lots of promises and dont deliver. They blow money on useless IR. They are greedy with options and shovelling them out to people who haven't done anything to deserve. They leak news to the point where news is no longer news. Yes what Phillip be has done to date is great but due to his

[Metalsguy1]

aww MercuryFilling...did I hurt your feelings? I can only assume you are just another profile for MoneyMouth - or you are just his chin wiping buddy. I love the way you so creatively mimic the buggy code that this site runs on. You and your pumper buddies are all the same and just continue slurping up whatever management serves you while you ignore the facts about the massive dilution and nest

[MoneyMouth]

This meme is for you metals. div.image { height: 300px; width:300px; content:url('https://i.imgflip.com/5yi4ew.jpg'); }

[Charly50]

Great post, moneymouth. I knew there were the suppositories.......   Papa, Papa Bio.... "Someone put something in my butt!!!"   Metals they take several at once. They are guaranteed to work. Toleikis ,with his good name, vouches for that!

[Metalsguy1]

oh Fraulein, how lonely you must be. Why don't you just wander down to the train station and lose yourself in the brothel for a month or two and gives us a break.

[AlfonzoBall]

I have not been to this board in a while. I'm confused Bio is Metals papa and Metals is a flat Pear?? What the hell is going on ?!?!?

[Metalsguy1]

Flat pear is an attempted insult by a German who is too stupid and lazy to learn English and doesn't realize that German idiots I mean idioms seldom have a direct translation. The rest is just an attempt by the resident pumpers to appear clever.

[Charly50]

Metals they misjudge the situation. They have thrown the stones. Not only against me, but against everyone. Now they complain that they are answered??   They are the aggressor, no one else. Fortunately in Canada there are many intelligent and nice people with decency.  You see,metals,intelligence knows no national borders and has nothing to do with nationality.  

[Mercuryfilling1]

Metals: You actually answered AlfonzoBall's "Flat Pear" reference, despite it being obvious that he was fully tongue in cheek??!! Too much! Better release about 30 psi out of Bio's giant inflated shlong...the breeze would do you good.

[Metalsguy1]

MercuryFilling? Are you not getting laid these days you seem to be obsessed with schlongs. If you need more filling you should hit up a fellow pumper.

[Metalsguy1]

MoneyMouth I know you must spend what little money you make on meth and lube but perhaps you could spend a little on a literacy course? Management may run the company but shareholders own it. Well we do for now, until the crack wh##s like you vote enough options until we are diluted out of existence.

[Mercuryfilling1]

Whichever level of discourse you engage in, Metallergic, that's where I'm happy to meet you.  My feelings hurt? Awwww...so nice of you to worry, but you should direct your empathy towards Bio. All those haters are turning him into a pot that calls the kettle black.  ... and remember 'allergic, you can only slam the "Post" button once - any more and you're'

[Canada2016]

Bioteck my apologies it's the holidays merry Xmas nothing wrong with profits whatever helps you sleep at night I just don't understand the name calling and ya you guys are probably right on being premature they always bait the pie in the sky need to deliver

[MustangSalley]

Canada, We all actually want this to succeed.  That was a classy aplogogy.  Hopefully January and 2022 is the year Sernova achieves milestones some of us have been waiting for a longtime. Merry Christmas and Happy Holidays to everyone....  MS

[Metalsguy1]

Gosh Canada are trying to steal the dunce cap we awarded to Fraulein? You are certainly the most transparent shill on the board. They don't need a 7th patient? That sure sounds like you have inside information. No one cares what Biotek says? Actually, quite a few people here respect what he has to say. He is right more than you shills are. Perhaps you should just focus on learning the