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StageZero Life Sciences Ltd T.SZLS

Alternate Symbol(s):  SZLSF

StageZero Life Sciences, Ltd. is a Canada-based vertically integrated healthcare company. The Company is focused on improving the early detection and management of cancer and other chronic diseases through diagnostics telehealth programs. Its lead product, Aristotle, is a mRNA multi-cancer panel for simultaneously screening for multiple cancers from a single sample of blood with high sensitivity and specificity for each cancer. The Care Oncology Clinic offers a supervised treatment regimen for people diagnosed with cancer of any type or stage. AVRT is a physician-led, telehealth program for identifying and managing the early warning signs of cancer and chronic disease. Its program includes a comprehensive online health evaluation; bloodtests to measure markers of inflammation and metabolism; an initial physician consultation; regular physician follow-up appointments and interval screening. Its additional cancer diagnostics include ColonSentry and the Prostate Health Index.


TSX:SZLS - Post by User

Comment by ScienceFirston Dec 04, 2020 1:24pm
48 Views
Post# 32038149

RE:RE:RE:The competition had been launched! Where's Aristotle???

RE:RE:RE:The competition had been launched! Where's Aristotle???OLDANUS007 is an uneducated "investor" with an obvious agenda.


From the GRAIL paper published in Nature  Research journal back in 2018, via a SPONSORED FEATURE (Sponsor retains sole responsibility for the content of this article):

 

In the validation data set, the multi-cancer early detection test had a false positive rate of 0.7% and an overall test sensitivity (true positive rate) of 54.9% (95% confidence interval [CI]: 51.0–58.8%). Sensitivity and 95% CIs by stage for all cancer samples with known tumour stage were: stage I (n = 185), 18% (13–25%); stage II (n = 166), 43% (35–51%); stage III (n = 134), 81% (73–87%); and stage IV (n = 148), 93% (87–96%). TOO was predicted for 96% of samples with cancer; of those, the prediction was correct in 93%. TOO accuracy was not affected by cancer type or tumour stage. These results demonstrated that a targeted methylation-based multi-cancer early detection test using a machine-learning classifier can simultaneously detect more than 50 cancer types with a single, fixed, low false positive rate of less than 1%, and can accurately localise the TOO13.
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