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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Comment by SPCEO1on Apr 16, 2021 11:42am
90 Views
Post# 33011092

RE:NASH issues

RE:NASH issuesYou might have heard Paul claim they could be the best in class drug in NASH on the conference call. That will all depend on whether the competitors are able to successfully complete their trials. If MDGL gets approved, it will likely be a very tough competitor. But they are not approved yet, so there is some (although not a lot) uncertainty still on that front. And we have also not yet seen how effective Egrifta might be in the general NASH population. And it has a clean safety profile. So, let's see how thinks work out over time. And there is still a lot of time before we can answer these questions concretely.

The F8 pen injector greatly reduces the injection versus oral obstacle. It is still there but those pens are simple and easy to use.

On pricing, there is no way the current price of Egrifta in the small lipo market is going to be utilized in the giant general NASH market. Egrifta's price will be lowered to a pont where it is competitive (assuming there is competition). 

jeffm34 wrote: 1. Competition 
2. injection vs oral formulation 
3. Pricing

All three of those will severely limit market potential. 


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