How To Save A Drug After A Negative Panel Review?Narrow the indication. It seems pretty clear that this is the step forward that needs to be taken. I found this quote from the FDA especially encouraging:
if a compound has activity “it’s incumbent on us” to work with the sponsor to try to get the drug to the public for areas of high unmet medical need.
https://www.futureofoncology.com/how-to-save-a-drug-after-a-negative-panel-review-narrow-the-indication-2/