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Claritas Pharmaceuticals Inc V.CLAS.H

Alternate Symbol(s):  CLAZF

Claritas Pharmaceuticals, Inc., formerly Kalytera Therapeutics Inc, is a biotechnology company that is focused on developing R-107 for the treatment of vaccine-resistant coronavirus disease (COVID) strains. The Company’s products in development include R-107 for coronavirus disease and Viral Infections, R-107 and Vaccines, and CLA-1816 for treatment of pain. R-107 is designed to defeat COVID viruses on contact. R-107 targets the Achilles heel of COVID, the spike protein on the surface of the virus. R-107 releases nitric oxide, which attaches to a specific amino acid on the spike protein, thereby disabling the spike protein. The CLA-1816 provides effective pain reduction, without the risks of addiction or respiratory suppression that exist with opioid analgesics. CLA-1816 strongly binds with and activates the alpha3 glycine pain receptor in the spine. The Company has leased a laboratory, office, and archival space in Beverly, Massachusetts.


TSXV:CLAS.H - Post by User

Comment by WORKINMONTANAon Mar 03, 2021 6:43am
229 Views
Post# 32702620

RE:We were counted as down and out 8 months ago, we were never

RE:We were counted as down and out 8 months ago, we were never

(LINK)https://pubmed.ncbi.nlm.nih.gov/23562771/
 

 

Abstract

Gaseous nitric oxide (gNO) is an approved vasodilator drug for inhalation up to a maximum dose of 80 ppm. While gNO has been shown, in vitro, to be an effective antibacterial agent (at 160 ppm), NO-donor compounds have been shown to inhibit a variety of viruses at varying stages of replication. This research was done in order to determine whether gNO at 80 or 160 ppm possesses an antiviral effect on influenza viruses. Three strains of influenza (A and B) were exposed to gNO for up to 180 min, before and after infection of MDCK cells. In search for possible mechanism of antiviral action, Neuraminidase (NA) inhibition assay of H1N1 that was exposed to gNO was performed. Results show that when virions were exposed to gNO prior to infection a complete inhibition of infectivity was achieved for all three strains. Post infection exposure of influenza with gNO resulted in about 30% inhibition of infectivity. Further testing showed that when eliminating the pH effect by exposing a dried virus to gNO, 90% inhibition was found after 2h exposure. NA activity, of whole dried H1N1 virus, was found to be inhibited by gNO (80%). These results suggest that 80 and 160 ppm gNO have a time dependent antiviral effect on influenza strains of viruses during various stages of cellular infection, which are not due to concomitant changes in pH in the surrounding milieu. Viral NA inhibition by gNO was shown and may be responsible for this antiviral effect.



Dude51 wrote: coming back. There was nothing like that punch in the gut when you read Barda canceled the deal with Salzman, KLY was no longer buying Salzman. Then all the bs about KLY being 50 or 70 million in debt,  we were just a shell company blah blah blah. Look at us now, more important, look at your bank account. It’s still way up, right? Were back but if you sell the shorters win.  Do not sell my friends.  Look at the bashing and bs that went on before the halt and all the bs and bashing after the halt, it’s just noise.
 
Somehow we made it back, it’s a miracle, hal a loolya, praise the lord, whatever, it’s just noise, ignore. The end game is what happens during the next 10 months, basically till the end of our trial on the humans in Australia.  Wait it out and you will be rewarded big.  This is going to really pop one of these days and it will be on good news, like FDA is fast tracking R-107, that would be a game changer imo.
 
Some have said this has already happened. Please provide link because I am quite sure if FDA specifically said they were fast tracking R-107,  maybe mentioned KLY or Claritas or even Salzman that would be bonus to us. Since imo this endorsement has not happened, I am however convinced that it will and therefore willing to wait another year roughly.
 
Why do I believe? Because I like the Salzbros, these are very smart people and from what I have read about Andrew Salzman is he is a genius. Were in partnership with Andy and the group, were in good hands, just have to be patient.
 
There is one thing you can do while waiting, tie up your shares up so the shorters can’t use them to short your shares right back at you. Put in a sell for say 20.00 and let it run max time and when that runs out repeat basically till you sell. Just remember when you go to sell you have to cancel the fake sale first and that takes a bit of time so time out your real sell.
Oh one last point, watch SaNOtize as our canary in the gold mine. Health Canada even likes them.
 
https://apnews.com/press-release/business-wire/science-business-public-health-products-and-services-coronavirus-pandemic-d6bf385141184700a2bde035c6b47678
 
 GLTA. Patients is key


 

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