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Ceapro Inc V.CZO

Ceapro Inc. is a Canada-based biotechnology company. The Company is involved in the development of extraction technology and the application of this technology to the production of extracts and active ingredients from oats and other renewable plant resources. Its primary business activities relate to the development and commercialization of natural products for personal care, cosmetic, human, and animal health industries using technology, natural, renewable resources, and developing products, technologies, and delivery systems. The Company's products include a commercial line of natural active ingredients, including beta glucan, avenanthramides (colloidal oat extract), oat powder, oat oil, oat peptides, and lupin peptides, a commercial line of natural anti-aging skincare products, utilizing active ingredients, including beta glucan and avenanthramides and veterinary therapeutic products, including an oat shampoo, an ear cleanser, and a dermal complex/conditioner.


TSXV:CZO - Post by User

Comment by prophetoffactzon May 18, 2024 5:34pm
33 Views
Post# 36047531

RE:RE:RE:Perplexity Ai on CoQ10 research in 2024:

RE:RE:RE:Perplexity Ai on CoQ10 research in 2024:CZO had this in bold letters in its November earnings release as if to highlight it:

"...additional research at McMaster University clearly showed that PGX-YBG gets into the macrophage cell. This important finding further supports the potential of YBG to act as a stand-alone and/or a carrier for other bioactives when transported by macrophages cells."


prophetoffactz wrote: Yes, the search results suggest that impregnating coenzyme Q10 (CoQ10) inside yeast beta glucan could potentially act as a "Trojan horse" delivery system to enhance the therapeutic effects of CoQ10 by improving its bioavailability and targeted delivery to immune cells like macrophages. Here's how:
  1. Beta glucan can bind to specific receptors on macrophages and other immune cells. This allows the beta glucan particles to be internalized by these cells through receptor-mediated endocytosis.
  2. By encapsulating or impregnating CoQ10 within the beta glucan matrix, the hydrophobic CoQ10 molecules can essentially "hitchhike" their way into macrophages and other immune cells along with the beta glucan carrier.
  3. Once inside the immune cells, the CoQ10 can exert its antioxidant, anti-inflammatory, and immunomodulatory effects more efficiently due to the enhanced intracellular delivery facilitated by beta glucan.
  4. This targeted delivery system could improve the bioavailability and therapeutic efficacy of CoQ10, especially in conditions where macrophages and oxidative stress play a key role, such as chronic inflammation, cardiovascular diseases, and certain cancers.
  5. The synergistic combination of beta glucan's immunomodulatory properties and CoQ10's antioxidant effects within the same immune cells could provide enhanced therapeutic benefits compared to administering them separately.
In summary, by exploiting beta glucan's ability to bind to immune cell receptors and facilitate intracellular delivery, impregnating CoQ10 inside yeast beta glucan can potentially act as a "Trojan horse" system to enhance CoQ10's bioavailability, targeted delivery to immune cells like macrophages, and overall therapeutic efficacy


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