Sirona Biochem Corp V.SBM

Annual Shareholder meeting Jan 25/11

[senatorice]

SIRONA BIOCHEM CORP.

Suite #950– 789 West Pender Street

Vancouver, British Columbia

V6C 1H2

Telephone: [phone]

Facsimile: 604-568-7704

AMENDED NOTICE OF ANNUAL GENERAL AND SPECIAL MEETING OF

SHAREHOLDERS

TO THE SHAREHOLDERS:

TAKE NOTICE that the 2010 Annual General and Special Meeting (the “Meeting”) of the

shareholders of Sirona Biochem Corp. (the “Company”) will be held at Suite 700, 595 Burrard Street,

Vancouver, British Columbia, V7X 1S8, is Tuesday, January 25, 2011 at 3:30 p. m. (Vancouver

time) and not Friday, January 25, 2011 as previously disclosed in the Notice and Information Circular

dated December 17, 2010.

The Information Circular previously delivered in connection with the Meeting remains valid.

DATED at Vancouver, British Columbia, this 31st day of December, 2010.

BY ORDER OF THE BOARD OF DIRECTORS

“Mark Senner”

Mark Senner

President and Director