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Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  V.TLT.WT | TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called Photo Dynamic Compounds (PDCs) and activates them with patent pending laser technology to destroy specifically targeted cancers, bacteria and viruses. The CLT division is responsible for the Company’s medical laser business. The Cool Laser Therapy division designs, develops, manufactures and markets super-pulsed laser technology indicated for the healing of chronic knee pain. The technology has been used off-label for healing numerous nerve, muscle and joint conditions. The Company develops products both internally and using the assistance of specialist external resources.


TSXV:TLT - Post by User

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Comment by macman1519on Jan 28, 2018 1:18am
81 Views
Post# 27448863

RE:April 28, 2016 AbbVie Buying Cancer Drug Startup Stemcentrx

RE:April 28, 2016 AbbVie Buying Cancer Drug Startup Stemcentrx Hemanluvsuman!!!! Now ur talking cash that we could have gotten at the 90 FUKIN great day results that Roger has not discussed, explains their significance or said much of anything about!!! Below is what we r missing because someone doesn't believe in our science our results???? Doesn't know how to write the right nr??? Doesn't understand the concept of seeking a closed bid and the benefits????? I don't know the reasons for Roger not seeking a JV in a closed bid manner, nor do I know what he thinks about our results and how those results show the way to our future direction!! I'm a mushroom and I only know Shitttt!!! Get pharma on board and below is our future starting on Monday when Roger puts out one nr!!!! Gee, thats tuff to do guys, rog will need some time to go back and forth on this one!!! quote=hemanlovesheman]It didn't seem to me that this was posted by anyone before, but if so, I might've missed it. This company, which was backed by Peter Thiel's Founders Fund, targets solid tumours in small cell lung and ovarian cancer, but I still think it's far below Theralase's overall technological advantage. They got bought out for 9.8 billion + the 400 million cash pile that Stemcentrx originally had, and this happened about 8 months after they demonstrated some efficacy (couldn't quite find the exact numbers, so perhaps Bencro could dig up some more info and data on this) in their phase one trial results. I think that there is a reasonably good chance that our time will eventually come if even a company that targets solid tumours like Theralase but is far inferior in its science can be bought out in the double-digit billions.

AbbVie Buying Cancer Drug Startup Stemcentrx for $10.2 Billion


By DAN PRIMACK 
April 28, 2016

Pharma giant AbbVie Inc. this morning said it will acquire privately held cancer drug developer Stemcentrx in a blockbuster deal that could be worth up to $10.2 billion. Not only would that make this one of the largest biotech acquisitions in recent memory, but also one of the five biggest sales ever of a venture capital-backed company.

AbbVie (ABBV, +13.72%) will pay $5.8 billion up-front in a combination of cash ($2 billion) and stock. Then there is up to another $4 billion in cash-based earn-outs, based on the achievement of various milestones. That brings the deal value to $9.8 billion, but Stemcentrx also has cash on hand that would be returned to shareholders, thus giving the company an entire enterprise value of around $10.2 billion.

The transaction is expected to close later in Q2.

San Francisco-based Stemcentrx currently has five drug candidates in clinical trials, each focused on targeting and eliminating the cancer stem cells that are responsible for tumors. The furthest along is designed to treat small-cell lung cancer, which accounts for between 10% and 15% of all lung cancers, and is one of the most likely to return after initial treatment. Last August, Stemcentrx published Phase I clinical trial results that showed, among other things, an unusually high percentage of sustained tumor size reductions among small-cell lung cancer patients who had initially responded to treatment, but then later relapsed.

“The addition of Stemcentrx and its late-stage compound Rova-T provide AbbVie with a unique platform in solid tumor therapeutics and complement our leadership position in hematologic oncology,” said AbbVie chairman and CEO Richard Gonzalez in a statement. “We believe the acquisition of Stemcentrx will strengthen and accelerate our ability to deliver innovative therapies that will have a remarkable impact on patients’ lives.”

Stemcentrx was founded in 2008 by CEO Brian Slingerland, a former investment banker, and chief scientific officer Scott Dylla, who previously had been a senior scientist with Oncomed Pharmaceuticals (OMED, -1.73%).

Stemcentrx initially raised a few small rounds of VC funding from firms like Western Technology Investment and Artis Ventures, before securing a $42 million Series D round in 2012 at around a $300 million valuation. That deal included a $30 million lead investment by Founders Fund, which would eventually become Stemcentrx’s largest outside shareholder, investing a total of around $300 million (making it the Peter Thiel-affiliated firm’s largest single investment, even larger than its commitments to Elon Musk’s SpaceX).

“We weren’t space experts and wouldn’t have done SpaceX if Elon wasn’t running it,” explains Brian Singerman, a partner with Founders Fund. “This was similar for us in that we’re also not cancer experts, but the founders were so strong and the science was so sound.”
Singerman adds that Founders Fund brought three research oncologists and three clinical oncologists into due diligence sessions before making its initial investment. “Scientists are usually very conservative, but we knew that Stemcentrx really had something when these oncologists told us, ‘Well, it won’t obviously not work.'”
Stemcentrx would go on to join the “unicorn” club in late 2014 and then be valued at around $5 billion in an August 2015 investment co-led by Fidelity Investments and Sequoia Capital. Fidelity recently marked down that investment by 37.76%, although the AbbVie deal represents a gain even before any of the earn-out is realized.

 
This Is How Sean Parker Plans to Fight Cancer
His personal connection to autoimmune diseases is leading the charge.
 

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