RE:Princess Margaret's Phase 2 Clinical Trial ConsortiumThere really is a very well structured network for Ph. 2 clinical trials to advance new technologies faster to bedside and mainstream, to the benefit of patients.
Our US sites for our NMIBC Ph. 2b (or any other future cancer indications like GBM) will all be "
xxxxxx Cancer Center", as per the NCI naming and because our partner Princess Margaret Cancer Center is part of the NCI group.
Like:
MD Anderson Cancer Center
Dana Farber Cancer Center
Memorial Sloan Kettering Cancer Center
Mayo Clinic Cancer Center
Roswell Park Cancer Institute
Stanford Cancer Institute
etc ...
Princess Margaret Cancer Centre is one of the Top 5 Cancer Research Centres in the World We have leveraged our clinical trials expertise to form and lead The Princess Margaret Phase II Consortium, which is a network of 12 cancer centres across Canada and the U.S. This is the only site outside of the U.S. to secure a contract with the U.S. NCI. Why the Cancer Centers Program is Important to Cancer Research
The NCI grant funding to the cancer centers supports shared research resources, provides developmental funds to advance scientific goals, and fosters cancer programs that draw investigators from different disciplines together. In addition, individual cancer center investigators are highly successful at obtaining research funding from NCI and other funding agencies and organizations. Indeed, research proposals from cancer center investigators account for about three-quarters of the successful investigator-initiated grants that are awarded by NCI.
And if we'd have to do a Ph. 3 (which we won't need to, as per FDA and HC), that would extend among these 900 community sites:
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Claridge - (5/22/2019 6:28:37 PM) Princess Margaret's Phase 2 Clinical Trial Consortium We're kind of priviledged, when you look at these numbers from PMH. And it's telling that UHN supports us for a minimum of 6 officially announced cancer indications.
Only one in approximately 10 drugs that come forward for testing at Princess Margaret Hospital are considered safe and successful enough to move on to larger clinical trials (10 years ago, that ratio was closer to 1 in 20).
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PHASE 2 CLINICAL TRIAL CONSORTIUM
Established in 2001, The Princess Margaret's Phase 2 Clinical Trial Consortium is one of seven sites – and the only site outside of the U.S. – to have received funding by the National Cancer Institute.The consortium's mandate is to develop leading-edge clinical trials through collaboration with other cancer centres across Canada.
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For bladder cancer, there's already this network of canadian hospitals:
Bladder Cancer Canada - 14 canadian hospitals
Find an NCI-Designated Cancer Center