Signing up new trial patients
If you put yourself in the shoes of someone who was told that they have bladder cancer, and may possibly lose their bladder or worse, it becomes easier to see why it is difficult to sign people up for the clinical trial. If your doctor says that the standard protocol is BCG, even with low success rates, then a person is more likely to follow that path than possibly risk their life on this unproven treatment.
I would ask "how many people have taken this treatment and what is the outcome?". It's a catch 22. There aren't enough results to make most people comfortable with trying this. 450 days is a long time if cancer has a chance to grow.
Hopefully when the small current sample has more results, it will help to create some momentum. The doctors need to believe in it.