RE:RE:RE:# of NR patients A small correction as from 1st set of 12 only 6 were NR, not 9, as 3 were CR and 3 were PR, sot that would still be only 6 out of 28 are NR at 90 days on all optimized treated patients. Still awesome rest are either CR or PR. IMHO
enriquesuave wrote:
To complete my point, at 90 days if we end up excluding at least 10 -11patients ( 9 NR from 1st set, plus patient who died and #4 from PH1) who can be considered severely undertreated or anomalies, then we would say out of the remaining 28 optimized treated patients, we have 3 NR's ( 13-10=3) . Please correct me if wrong, but that is pretty damn good IMHO. Already 35% CR at 360 days is damn good and better than All single agents including CG007 (28%). Plus we have 12% PR which can convert in part or all to CR.
enriquesuave wrote: Nice observations. If we only look at the NR patients at 90 days, the include 1 NR fro PH1B ( pt had prior metastasis and not really eligible) 1 patient who died of HF ( had optimized treatment) 5 patients who were wrongly dropped from trial ( 1st set of 12 undertreated) plus 3 patients from remaining 7 of 1st set of 12 who never got an Optimized Treatment ( only 4 I believe got a second treatment which was optimized. ( so over all 9 NR from 1st of 12 plus 1 from PH1 and patient who died). That's 11 patients who should not really be included in trial data IMO, but are . We are seeing improvement over time so this looks very good IMHO. Also 4 more patients have been treated as we now stand at 45 patients total ( includes 3 from PH1). In May there was only 41 patients total. 7 now pending at 90 days. Looking forward to Next update