RE:RE:Adstiladrin data shown at end of Nov at big UroOncology meet
The more I think of it this is the worst data for adstiladrin. I really shows that you do all these expensive bladder instillations (6 induction plus 12 per year for total of 30 in 3 years) and no patient really gets to feel like they are in the clear. By 3 years there is only a 1/8ish chance of being CR still.
In a way it is lucky to have this data BEFORE BTD submission as now TLT can really sell the application with that reference material. I'm really hoping that the 18 month data ( which already exists out there as all 14 CR's to date are past 18m) will show that the 14 CRs at 450 are still CR at 540. If so then it would be the only agent that has a sustained CR after you are done the protocol. If you look at all patiets that are green CR 3 in a row, only 11% fall off (i.e. 270-365) and 100% of the 4 in a row CR's stay that way to 450. At 450 they would have been 9 m out from last intervention. Cool.