RE:RE:RE:McFarland & Lilge Improve radiation-activated PDT(radio-PDT)
Agree that this is nice to see but changes litte for now.
If they can get a GBM 1a trial going then that would lead to some good near term information on the efficacy of this therapy. GBM grows so fast and the 1a trial would be in the end-stage, near death patients that you would have some fairly quick evidence if therapeutic or not (3-6m timeline).
Assume that looks good, then you would have a pretty fast track for GBM since so little help late stage GBM.
Then would just need to pick one other solid cancer to show that same principal applies. That would open window to big indication. Not just one cancer but a whole category of cancers - solid ones.
Then these compounds such as in the article could be positioned as drug 2.0 and drug 3.0 with faster assessments based on the prior success of the first round.
All of this sounds fanciful. Im just saying that if they can get rolling on some GBM and it helps, then everything else is possible. Also shows that they are not a one-trick pony therapy (NMIBC).