Theralase Technologies Inc. V.TLT

BTD

[fredgoodwinson]

Thanks Dawg - looks sound to me. Correct me if I`m wrong but you`re saying that the results of the next set are already known and will alter these percentages very little?  This fact will surely not have escaped any of the relevant parties.

While these results suggest that the Company would be fairly granted BTD if an application were made now pitiful volume depth and momentum suggest an opposite dynamic. This begs the question as to what exactly is supposed to change for the better between now and the initiation of a BTD Application and exactly what is being said to the Company by the FDA to give it pause for thought?

[DJDawg]

Hi Fred, My opinion is more around the newest 450 day update, whenever that comes.   Looking on this graph, made from the poster (same data): https://postimg.cc/Yv0QHpLj patients 30 to 34 are the only ones pending with data to arrive at 450. Using my numbering from that graph 30  NR at 360 so hard to see any way that would change. NR at 450 31  CR at all time points so

[fredgoodwinson]

Thanks for clarifying Dawg - that`s what I thought you were saying. The failure to make a BTD Application becomes increasingly perplexing.

[Eoganacht]

Can't argue with that. 29.4% CR when the 360s hit 450 days and maybe 32% CR when all 37 patients at 270 days hit 450 days.

[enriquesuave]

The mere fact that  IR patients remain IR for so long makes me think that most or all may actually be CR.  CIS if still present would have been more manifest on bladder lining after so long and would be detected with cystoscope.  All IMHO  let's still not get too excited until they are properly reclassified one way or they other.  I want to see how the 11 pending

[Eoganacht]

If we just supposed, (keeping excitement firmly in check), that the 3 IRs at 450 days and the 2 at 360 days were all reclassified CR we would be at a 450 day CR rate of 44% at the next update.

[CancerSlayer]

I agree Enrique... Any persistent/prolonged IR is an indication to me that the cancer is being held in check for the most part, which I'd consider a reasonably good outcome for a cancer that has such a high risk of progression.  My guess is the immune response triggered by our treatment is not only holding these IRs in check, but the response may also become more robust over time

[Longholder99]

 The one thing that IR brings along with CR is time. Time is a luxury most cancer patients do not have.  Time with the organ affected still intact affording a normal.life.  Time among the living.  Time.   IR is a poignant achievement and worthy of many dollars in Market Cap.  IR with minimal side effects means more treatments for maintenance of the condition

[Longholder99]

Any Urologist that has a consistent group of patients coming in for PDT in a series of treatments for a tough NMIBC case will have a mega income stream.  Being among the first to adopt this procedure and become known as the Dr that let's you keep your bladder will be ridiculously wealthy.  Never mind the Dr who adopts the GBM procedure and is your key to remaining on the planet with