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Bullboard - Stock Discussion Forum
Oncolytics Biotech Inc
T.ONC
Alternate Symbol(s):
ONCY
Healthcare
Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and...
adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.
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Bullboard (TSX:ONC)
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(5618)
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Noteable
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Comment by
Noteable
on Sep 18, 2024 11:39am
RE:RE:How does Accelerated Approval work
This is for the benefit of Quentin30 - who doesn't own any ONCY stock BTW. " Accelerated approval (AA) targets candidates that are similar to those awarded BTD in terms of
...more
(5618)
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Comment by
Noteable
on Sep 18, 2024 11:25am
RE:RE:RE:RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
Furthermore Accelerated Approvals are becoming more frequently granted by the FDA on Phase 2 data with as little as 30 patients (not powered for statistical significance) - and thee AAs are also
...more
Northstar Gold Signs MOU with Hunan Nonferrous Ltd. to Develop Gold Resource
posted Sep 19, 2024 9:00am by
Northstar Gold Corp.
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The MOU grants Hunan Nonferrous the opportunity to explore and develop a near-surface NI43-101 gold mineral resource at Northstar’s 100%-owned Miller Copper-Gold Property, located 18 kilometers southeast of Kirkland Lake, Ontario. This will be achieved by diamond drilling up to 10,000 meters, allowing Hunan Nonferrous to earn a negotiated interest in the resultant NI43-101 gold resource. ...read more
(96)
•••
Quentin30
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Comment by
Quentin30
on Sep 18, 2024 11:14am
RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
and Matt and Prof Heineken already told us that Bracelet-1 was not powered for statisical significance. How many patients were in each arm? lets just remind the boys and girls shall we.. Bracelet-1
...more
(5618)
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Comment by
Noteable
on Sep 18, 2024 11:13am
RE:RE:RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
Quentin30 while IND-213 as a study wasn't powered for statistical significance, because of the low number pf patients enrolled, the trial's results were statistically evaluated showing a
...more
(5618)
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Noteable
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Comment by
Noteable
on Sep 18, 2024 11:02am
RE:RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
You don't seem to understand much. ONCY's 180-200 patient Phase2b->Phase3->Confirmatory trial is an adaptive designed trial that can seemlessly move from one Phase to the next Phase
...more
(96)
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Quentin30
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Comment by
Quentin30
on Sep 18, 2024 10:57am
RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
and Matt and Prof Heineken already told us that Bracelet-1 was not powered for statisical significance. How many patients were in each arm? lets just remind the boys and girls shall we... Bracelet-1
...more
(96)
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Quentin30
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Comment by
Quentin30
on Sep 18, 2024 10:48am
RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
and yet they need a third phase II trial... that's three phase II trials... to show something that in the majoraity of cases is approved for AA with just one... Puts ONCY in the minority
...more
(5618)
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Noteable
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Comment by
Noteable
on Sep 18, 2024 10:47am
RE:RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
Once again the major determinant of clinical benefit for the FDA is overall survival (OS) which was statistically significantly improved in both of ONCY's IND-213 and Bracelet-1 mBC Phase 2
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(5618)
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Comment by
Noteable
on Sep 18, 2024 10:32am
RE:RE:RE:RE:RE:ONCY's Bracelet-1 was in HR+/HER2 negative breast cancer
ONCY has demonstrated that PFS was 38.2% better in the pelareorep + paclitaxel treatment arm of Bracelet-1 vs the control arm of paclitaxel alone and reproduced a near doubling (2X) median overal
...more
(96)
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Quentin30
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Comment by
Quentin30
on Sep 18, 2024 8:59am
RE:RE:RE:RE:RE:RE:Quentin30 is a pathological prevaricator.
BUT, in IND213 there was no differentiation in PFS between the test and reference arms, so that trial cannot be used to support AA. what are you not understanding about that?
(96)
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Quentin30
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Comment by
Quentin30
on Sep 18, 2024 8:57am
RE:RE:RE:RE:RE:RE:Quentin30 is a pathological prevaricator.
as the CEO of ONCY, anything he said wasn't authorised by ONCY..? that's interesting... Kirk Look, the CFO of ONCY is talking to us about science... hmmm, is what he's telling us
...more
(290)
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inthno
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Comment by
inthno
on Sep 17, 2024 9:28pm
RE:RE:RE:RE:RE:RE:Quentin30 is a pathological prevaricator.
You seem to like putting people down. Hope that makes u feel better. As for AA , yes onc will go for it in the upcoming trial as they stated in the presentation but they did not mention after
...more
(75)
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Journeytc
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Comment by
Journeytc
on Sep 17, 2024 7:56pm
RE:RE:RE:RE:RE:Quentin30 is a pathological prevaricator.
I remember Brads 2016 presentation at the Richmond. Knives and forks clanging over his presentation. He spoke of reovirus as an activator for every biotherapeutic in
...more
(5618)
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Noteable
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Comment by
Noteable
on Sep 17, 2024 7:52pm
RE:RE:RE:RE:RE:Quentin30 is a pathological prevaricator.
Quentin30 Koffey what are you blathering about again? Brad Thompson hasn't been with ONCY since November 2016 .. so if you heard him saying anything in December, whatever it was it wasn'
...more
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