Pepmoron can't read can't add !!!! LOL!!!
Pepmoron wrote this:
At this stage, TLN is three years behind XL-184. This compound is inphase III for MTC and well into phase II for glioblastoma. Plus a phaseIb/II for lung cancer. All that with real response rate on asignificative number of patients. No comparaison possible at this timewith 4601. Also, XL-4601 is an oral drug to be taken once a day. 4
601is a very sort lived drug that need constant infusion (that means largequantity of the drug to be injected on a continuous mode). Pull outyour pink glasses dumbo and look at reality. It is pure ignorance orfraudulent behaviour to suggest that at this stage 4601 could get asimilar deal as XL-184. Stop writing stupidity here and if a few peopleare reading it with any interest. Do not believe a single word of thiscrappy stuff. It is one thing to hope for a small offer from a pharma,and suggesting that a pharma could be willing to offer up to
500M foran early stage drug with no real efficacy data (response rate).
Remember I provided this link
https://ir.exelixis.com/phoenix.zhtml?c=120923&p=irol-newsArticle&ID=1235491&highlight=
Now scroll down and read about
XL281 a phase I compound! and XL 184 a phase II compound.
There is actually 2 deals in same press release.
See how much they got for both.
Now, we all agree how TLN 4601 is now, before PII and after PI.
See what the results XL 281 got for it
will receive an exclusive worldwide license todevelop and commercialize XL281 and will be responsible for funding allfuture development. is eligible for development and regulatorymilestones of up to , sales performance milestones of up to and double-digit royalties on worldwide sales of XL281.
It is one thing to hope for a small offer from a pharma,and suggesting that a pharma could be willing to offer up to
500M foran early stage drug with no real efficacy data (response rate).
Two questions for Pepmoron - can you read?
Can perform basic mathematical operations?
Let's see if I compare TLN 4601 to XL 281, 315 + 150 + royalties = about 500 millions according to me.
Only reason why I compared it to XL 184 is that it's also a GBM drug. Remember Pepmoron thinks that there is no market for GBM no value for it...
. 4
601is a very sort lived drug that need constant infusion (that means largequantity of the drug to be injected on a continuous mode).
Check out Erbitux also an intraveneous injection drug.
https://en.wikipedia.org/wiki/Erbitux
So what ! People will take it any form of treatment because cancer is life threatning condition!
Conclusion : How are u suppose to evaluate (ie put a dollar figure) to a partnership deal ?
You compare it with a similar deal not too distant in time.
For 4601 you compared it with XL 184 or XL 281... Duhh....
Again pepmoron is a moron.