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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Bullboard Posts
Post by pericles1on Apr 05, 2012 10:34am
432 Views
Post# 19762712

Just listened to conference call!

Just listened to conference call!

Good conference call, Brad covered a lot of ground. First off he admitted they started the Phase III with half the enrollment rate that they predicted but with the number of sites growing they have the enrollment rate they need to finish by the end of the year. You don't mind Brad if I don't take that to the bank.

I learned a number of new facts, first off reolysin can hide in the red blood cells and be delivered to cancer when they transfer oxygen, never heard of that before. Also the cancer that starts growing after a response does not gain an immunity from reolysin which is what I thought. He's not sure why but it's not resistance at least per Brad. Also a significant problem which you don't think of in trials was labeling in 12 languages in Europe he sounded like it was a real pain.

He also covered patents, saying a couple challenges came from big pharma and they successfully defended. The way he sounded their will be more. This is one area that could cause a negative surprise in the future, I hope not but you never know.

He also said that data from stage I will be coming in the very near future, not sure what that means but it sounds soon.

He also said that enrollment for squamous cell of the lung was slower than expected which he did not understand at all. Pancreatic is actually enrolling faster than expected. They will make a decision on new lung trial this quarter.

Bullboard Posts