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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Comment by G1945Von Sep 30, 2020 8:28am
159 Views
Post# 31640529

RE:RE:RE:Discussions Involve Multiple Partners in Varying Formats

RE:RE:RE:Discussions Involve Multiple Partners in Varying FormatsQT, yes, I agree with your last comment. 

 
"Jardiance (co-owned by Boehringer Ingelheim and Eli Lilly) and Januvia (Merck & Co.) are the current SGLT2i and DPP4i market leaders, respectively. The market penetration of these treatments is expected to grow significantly over the next five years, with the potential global market value of approximately US$25 billion by 2024 (Mordor Intelligence 2019). However, no diabetes medication alone (including SGLT2i and DPP4i) has been shown to reduce MACE in patients with recent ACS and substantial residual risk remains for this population. " (Bolding and underscoring added to make the point)

It would be a missed opportunity for Jardiance and others not to take advantage of Apabetalone's synergy with SGLT2 inhibitors in reducing MACE in patients with (ACS) Acute Coronary Syndrome. 


G1945V
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