RE:1st publication of Phase I trial now available online11, 9, 24, 24, 12, 18 are the numbers of unsuccessful BCG doses our patients 1-6 received before enrolling in our Ph. 1b.
So our 2-doses treatment is kind of revolutionnary, especially when considering that patient #5 (12 unsuccessful BCG doses) and patient #6 (18 unsuccessful BCG doses) were cancer-free after 1 dose (ph. 1b was only 1 dose).
BCG unefficacy (24 doses!!!) was probably responsable for the worsening condition ... and death of patient #4 when you think of all the time it gave to the tumor to go deeper and become metastasic. This patient paid the price and it's time for TLD-1433 to replace BCG.