RE:RE:Next week's trial result updateEoganacht wrote: It looks like we are headed for a 450 day CR rate of around 40% in 6 months. Is it possible Theralase is waiting for this result before submitting their BTD application - so as to remove all doubt about durable complete response?
Eoganacht wrote: Next week we should get an update on the trial results. The last one we got was on May 30 and looked like this:
CR 90 days | CR 180 days | CR 270 days | CR 360 days |
60% | 53% | 43% | 36% |
32 out of 53 | 26 out of 49 | 18 out of 42 | 14 out of 39 |
The CR rate at 450 days (33%) won't likely change as there weren't any patients diplayed on the swimmer's plot at 360 days waiting for their 450 day evaluation. Here is the best case scenario we could see next week. This assumes that all of the 5 patients waiting for their 90 day evaluation are CR.
CR 90 days | CR 180 days | CR 270 days | CR 360 days |
64% | 53% | 49% | 38% |
37 out of 58 | 28 out of 53 | 24 out of 49 | 16 out of 42 |
We will have to wait a while to see a big improvement in the 450 day results: The May 30 results looked like this:
CR 450 days |
33% |
13 out of 39 |
In 6 months, if all goes well. the 450 day results could look like this:
CR 450 days |
41% |
20 out of 49 |
Good chance we'll see 450 days between 40.5% - 42.8%
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