RE:RE:RE:RE:RE:RE:RE:Exploring NMIBC Options in the face of BCG Shortages
Regrets on being late to the gem/doce discussion.
The protocol for the main study that I could find using gem/doce was
- 6 instillations, weekly for induction
- monthly up to 24 months
What is confusing about the main article is that it doesn't list anywhere (Eog, maybe you can see it) how many treatments the patients got so I'm going to have to assume that many/most got the monthly instills for up to 2 years.
I have such a hard time being impressed by something that maintains its CR rate by give the repeat treatment monthly and then quoting durable CR. It is just not as impressive as a treatment that has been given and then stopped with durable CR AFTER the last treatment. The nature of cancer is that it can often been smacked down but all it takes is one residual cancer cell to restart the entire process of growth and spread. So Ruvidar is still way impressive in terms of what it offers compared to monthly instills going on and on.