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COSCIENS Biopharma Inc T.AEZS

COSCIENS Biopharma Inc., formerly Aeterna Zentaris Inc., is a specialty biopharmaceutical company engaged in the development and commercialization of a diverse portfolio of pharmaceutical and diagnostic products, including those focused on areas of unmet medical need. Its lead product, macimorelin (Macrilen; Ghryvelin), is an oral test indicated for the diagnosis of adult growth hormone deficiency (AGHD). The Company is also engaged in the development of therapeutic assets and proprietary extraction technology, which is applied to the production of active ingredients from renewable plant resources used in cosmeceutical products (i.e., oat beta glucan and avenanthramides, which are found in skincare product brands like Aveeno and Burt’s Bees formulations) and being developed as potential nutraceuticals and/or pharmaceuticals.


TSX:AEZS - Post by User

Comment by prophetoffactzon Jun 19, 2024 9:48am
52 Views
Post# 36095732

RE:RE:Safety/tolerability profile

RE:RE:Safety/tolerability profile

CZO mentioned that it also combined avenanthramide with one of its newer PGX carriers with promising results. The current pill trial may be a building block to greater things as PGX also reaches the decision point for mass industrialization. A recent paper by another group combined yeast beta glucan with avenanthramide with interesting results. CZO has also been working with the Angiogenesis Foundation on CZO's beta glucan and avenanthramide and Gilles called the results a home run for wound healing. Could that benefit a cardiovascular drug? Could the avenanthramide pill be used with the oat beta glucan chewy product? Who knows... This was also mentioned by the Angiogenesis Foundation:

August 2021:

“Endothelial cell stimulation is a hallmark of, and a requirement for, wound healing,” commented Dr. Vincent W. Li, Chief Scientific Officer of the Angiogenesis Foundation. “Given that Ceapro products have demonstrated in vitro activity that may impact healing at the cellular level, we expect to further characterize this biological activity using well-established in vivo models and assess their potential applications to a variety of functional health benefits. These benefits include tissue regeneration and repair as well as disease conditions such as COVID-19 and post-COVID-19, which are associated with severe blood vessel damage leading to thrombosis in the lungs and other organs. We believe this has the potential to address a root cause of such complications.”

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