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COSCIENS Biopharma Inc T.AEZS

COSCIENS Biopharma Inc., formerly Aeterna Zentaris Inc., is a specialty biopharmaceutical company engaged in the development and commercialization of a diverse portfolio of pharmaceutical and diagnostic products, including those focused on areas of unmet medical need. Its lead product, macimorelin (Macrilen; Ghryvelin), is an oral test indicated for the diagnosis of adult growth hormone deficiency (AGHD). The Company is also engaged in the development of therapeutic assets and proprietary extraction technology, which is applied to the production of active ingredients from renewable plant resources used in cosmeceutical products (i.e., oat beta glucan and avenanthramides, which are found in skincare product brands like Aveeno and Burt’s Bees formulations) and being developed as potential nutraceuticals and/or pharmaceuticals.


TSX:AEZS - Post by User

Post by prophetoffactzon Jul 05, 2024 1:34pm
58 Views
Post# 36120047

Oat beta glucan pill and wound healing?

Oat beta glucan pill and wound healing?Ceapro's oat beta glucan could potentially be used for wound healing, in addition to its cholesterol-lowering effects, based on the following evidence:
  • Studies have shown that oat beta glucan is highly effective in stimulating collagen synthesis and can play a prominent role in skin restructuring and wound healing.
  • In a recent animal study, 1% oat beta glucan treatment resulted in earlier wound closure in mice compared to controls. The BG-treated tissue exhibited more microvessels (angiogenesis) and the presence of endothelial progenitor cells. BG treatment also resulted in increased collagen fiber width and length, more resembling normal tissue architecture compared to scar tissue.
  • The researchers concluded that oat-based bioactives like beta glucan exhibited potential to improve regenerative wound healing, reduce inflammation, promote angiogenesis, and reduce scar formation.
  • Ceapro is developing oat beta glucan beyond the personal care market into the nutraceutical and/or pharmaceutical space to target metabolic diseases. A cholesterol-lowering clinical trial is currently underway.
So while the current clinical trial is focused on cholesterol reduction, Ceapro's oat beta glucan could potentially be repurposed or further studied for its wound healing properties, given the promising preclinical data. However, additional clinical research would be needed to demonstrate its efficacy for wound healing in humans.
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