RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE: Pelareorep + Paclitaxel = ADC/HER2 failed breast cancerBerry et.al. (2020) " ...data demonstrate that crosslinking chemotherapeutic agents to oncolytic viruses facilitates functional drug delivery to cells targeted by the virus, making it a viable approach for combination therapy against TNBC."
" Reovirus oncolytic efficacy is further augmented by combination with topoisomerase inhibitors .." .. similar to the topoisomerase inhibitors conjugated in both HER and TROP2 antibody drug conjugates (ADCs).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493048/