RE:RE:Pelareorep in 3rd line HR+/HER2 negative breast cancerAn ASCO Meeting Abstract from the 2022 ASCO Annual Meeting has cited that the average cost for the first year of HR+/HER2 negative was US$192,367 per patient. With ONCY stating that approximately 55,000 women would become eligible for 3rd line pelareorep + paclitaxel treatment, and a per patient cost of US$192K, this patient group would translate into approximately US$10.56 Billion in annual sales opportunity for pelareorep or a significant percentage of this gross sales value, in HR+/Her2 – mBC, that ONCY or a Big Pharma acquirer of ONCY would seek to achieve.
https://ascopubs.org/doi/10.1200/JCO.2022.40.16_suppl.e18834
The long view is eventually moving pelareorep into first line therapy in combination with a variation of immune checkpoint inhibitors +/- bispecifics +/- ADCs +/- small molecule inhibitors +/- CAR-T therapy,