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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > CAR-T update
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Comment by Noteableon Jan 08, 2025 12:45pm
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Post# 36394494

RE:RE:RE:RE:RE:CAR-T update

RE:RE:RE:RE:RE:CAR-T updateJanuary 08, 2025 -  Roche Nears Completion of CAR-T therapy company Poseida Acquisition for $1.5B

Poseida's allogenic (off-the-shelf) CAR-T therapy is in Phase 1 clinical studies for the treatment of 'liquid'  (blood) cancers, including multiple myeloma and B-cell lymphomas.

Conversely, ONCY has demonstrated that pelareorep + CAR-T therapy can affect a complete response in the treatment of solid tumors. 

https://www.biospace.com/business/roche-buys-poseida-for-up-to-1-5b-leaning-into-off-the-shelf-car-t

[ As previously reported MAYO's Dr. Richard Vile has demonstrated that ONCY's pelareorep is putatively capable of modifying a patient's T cells directly within their body to potentially affect a "cure" through the administration of a CAR-T therapy + pelareorep followed by a single IV delivered pelareorep 'boost' ]

https://www.postbulletin.com/business/vyriad-signs-huge-deal-with-novartis-to-develop-new-cancer-treatments
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