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Protalix Biotherapeutics Inc PLX

Protalix BioTherapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of recombinant therapeutic proteins expressed through its proprietary plant cell-based expression system, ProCellEx. In addition, the Company is developing PEGylated uricase, or PRX-115, for the treatment of severe gout, Long Acting (LA) DNase I, or PRX-119, for the treatment of NETs-related diseases, and other technologies and preclinical assets. Its product, Elelyso is an enzyme replacement therapy (ERT) for the treatment of patients with Gaucher disease. Its ProCellEx platform is being used to manufacture both of its approved and marketed products as well as PRX-115 and PRX-119. PRX-115, a plant cell-expressed recombinant PEGylated Uricase (urate oxidase)- a chemically modified enzyme under development for the potential treatment of severe gout. PRX-119 is a plant cell-expressed PEGylated recombinant human DNase I product candidate.


NYSEAM:PLX - Post by User

Post by skyhigh123on Mar 14, 2018 11:18am
164 Views
Post# 27713223

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Protalix: It's Time To Sell

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2 comments
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 About: Protalix BioTherapeutics, Inc (PLX)
 

Summary

Protalix announced the results of their phase 2 open label trial of OPRX-106 for the treatment of Ulcerative Colitis on March 13.

The results are positive, but there is an important omission.

The company did not address why 6 out of 24 (25%) enrolled patients did not complete the trial.

Like PRX-110's CF trial, OPRX-106's UC data only provides early evidence of efficacy.

If partnerships are not secured, dilution risks are most likely to fund further operations.

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